|Organization:||International Science and Technology Center, Russia, RU|
|I.P. Brief:||The technology is a Nano-materials development and production technique for pure Titanium, Aluminum and other metals. |
|Summary of I.P.:||The technology is a Nano-materials development and production technique for pure Titanium, Aluminum and other metals. For pure titanium, the 2-step process significantly increases the strength compared to even alloys as Ti-6Al-4V.
Pre-production volumes (2,000 kg / year) are available today. Patent coverage in the US is good and extensive know-how backs the technology.
Pure titanium, desirable for use in a variety of medical and dental applications, including implants, is chemically and biologically more compatible with human fluids and tissue. Early studies show patients recover 5x faster from surgeries with pure-Ti. However, pure-Titanium has been too weak for weight-bearing prostheses, as found in leg or hipbone implants, as the strength of pure titanium is less than half the strength of Ti-6Al-4V alloy. Russian researchers have increased the strength of pure Nano-titanium to levels more than twice that of Ti-6Al-4V alloy. The use of pure Nano-Ti will reduce the thickness and weight of weight-bearing implants by approximately 20-30%, with the same percentage cost reduction expected, since Nano-Ti can be produced with on-par unit-volume costs as (regular) pure Ti and Ti-alloys.
|Primary Industry:||Health & Medical Devices|
|Specific Market:||Medical and dental implant markets. Automobile industry, aeronautics|
|Market Size:||$42 billion medical devices market.
The US knee implant market, totaled over $1.1 billion in 2003. The US hip implant market, is expected to be greater than $2.0 billion in 2007.|
|State of the Art:||Early studies show patients recover 5x faster from surgeries. Titanium has been too weak for weight-bearing prostheses, as found in leg or hipbone implants. The strength of pure Nano-titanium is increased more than twice that of Ti-6Al-4V alloy. |
|Figures of Merit:||Because of the outstanding bio-compatibility of pure Nano-Ti as compared to Ti-alloys, weight bearing implants can be expected to last significantly longer (50% or more is the target) and can avoid the extremely painful end-of-life characteristics inherent with Ti-alloy implants. |
|Tech. Obstacles:||Istitute situated in Ufa, Russia
Certification by Russian Ministry of Health is in process not finished|
|Market Obstacles:||Adjusting and launching the pilot technology of production of Nanostructured semi-products for the industrial scale
For the production organization inputs for technical preparation of production, for new equipment purchase instead of depreciated one, for production certification and for additional floating assets, for redecoration of production sector.|
|Publications:||1. Valiev R.Z.// Nanostructuring of metals by severe plastic deformation for advanced properties // Nature Materials / VOL3 / August 2004 / www.nature.com/naturematerials
2. Valiev R.Z., Islamgaliev R.K., Alexandrov I.V. Bulk nanostructured materials from severe plastic deformation.// Progress Materials in Science. - 2000. – v.45. – P. 103-189.
3. T.C. Lowe and R.Z.Valiev, eds. Proc. NATO ARW Investigations and Applications of Severe Plastic Deformation, Dordrecht, Netherlands, Kluwer Publ., (2000).
4. V. Stolyarov, V. Latysh, R.Valiev, Y.Zhu, T. Lowe, The development of ultrafine-grained Ti for medical applications, Proceedings of the NATO ARW on Investigations and Applications of Severe Plastic Deformation (Moscow, Russia), NATO Sci. Series, eds. Lowe T.C. and Valiev R.Z., Kluwer Publ., 80, (2000), 367.
5. V. Stolyarov, L. Shestakova, Y.Zhu, R. Valiev Formation of metastable states in nanocrystalline Al- and Ti-based alloys by the SPTS technique, Nanostructured Materials, V.12, 5-8, (1999), 923.
1 Scientific Director of the project: Valiev Ruslan, Dr.Sci., Prof., Scientific Director at IPAM USATU;
2 Technical Director: Vladimir Latysh, PhD, Senior Researcher at IPAM USATU, chief engineer of Innovation Research and Engineering Center “ISKRA”.
It is suggested that new vacancies will be created for ~20 people|