Anergix, LLC

Location:CA, US
Speaker:David Graham
Title:General Manager
Primary Industry:Health & Medical Devices
Executive Summary:Anergix, LLC is developing a combined cell/gene therapy treatment for multiple sclerosis (MS), a disease that affects roughly 400,000 Americans and 2.5 million worldwide. The therapeutic strategy is to induce immune tolerance to one or more of the suspected antigens thought to cause the autoimmune response against the myelin sheath proteins surrounding nerve cells. Tolerance, or anergy, is a state of diminished immune response to a particular antigen. The value of the Anergix technology rests upon several important factors: (1) antigen specificity by using MBP or PLP peptides will not lead to the broader immunomodulatory effects seen by current Disease Modifying Therapies; (2) subcutaneous implants will eliminate the need for frequent im, sc or iv injections; (3) together, these first two advantages will mean fewer side-effects and better long term compliance on the part of MS patients. One aim of our clinical research program will be to establish efficacy of a single annual implant. If successful, the Anergix approach will benefit all MS patients, particularly those in rural settings (~30%) that are not treated today because of lack of access to comprehensive MS treatment centers comprising neurologists, nurses, social workers, and psychologists.
Venture is:A-Round


Corporate Symposium

Harvard OTD
Partner Sponsor

2008 Corporate Presentations

Air Products
  • BASF
  • Genzyme
  • Lockheed Martin
  • Sanyo

Event Sponsors

Jackson Walker

Collocated Events

June 1-5, 2008
Nanotech 2008
Clean Technology 2008
BioNano 2008

Press Sponsor

Business Wire

Commercialization Partner


Media Sponsors

(joint with Nanotech 2008) Nature
Red Herring

Supporting Organizations

Boston University
Midwest Research University Network


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