Biotech, Biomaterials and Biomedical: TechConnect Briefs 2017Biotech, Biomaterials and Biomedical TechConnect Briefs 2017

Diagnostics & Bioimaging Chapter 4

Amplification-free liquid biopsy by fluorescence approach

J. Uhd, M. Taskova, A. Okholm, K. Astakhova
University of Southern Denmark, Denmark

pp. 106 - 109

Keywords: liquid biopsy, ctDNA, fluorescence, diagnostics, bioimaging

Diagnostics of cancer associated ctDNA, BRAF V600E, KRAS G12D and KRAS G13D respectively. By the use of modern fluorescence microscopy and fluorescently labeled mutation specific LNA/DNA probes. Which resulted in a mutation specific detection.