IP Snapshot: Closed Loop Blood Glucose Control

The research team of Dr. Damiano and Dr. El-Khatib of Boston University has invented an algorithm for dynamically assessing and predicting glucose level in an individual to form the basis of a system for continuous glucose control.

Closed Loop Blood Glucose Control
Inventors: Edward Damiano and Firas El-Khatib, Boston University, Boston, MA, USA
Industry: Health & Medical Devices
Market: Type I diabetes/ICU
Technology Contact: Sean Lee, Office of Technology Development, Boston University

The research team of Dr. Damiano and Dr. El-Khatib has invented an algorithm for dynamically assessing and predicting glucose level in an individual to form the basis of a system for continuous glucose control. The algorithm is seen as an improvement over existing methods in that it requires only input of body weight, has less aggressive control actions, and is more robust that other published methods.

Sean Lee of Boston University’s Office of Technology Development told TechConnect that a successful closed loop control has been demonstrated in diabetic pig models, and IDE approval and human clinical trials are expected to begin this spring. The goal is to establish closed loop blood glucose control as the standard of care in diabetes management for the appropriate patient groups.

The project is supported by Juvenile Diabetes Research Foundation and Wallace Coulter Foundation. The clinical trials will be conducted in cooperation with Massachusetts General Hospital, Abbott, and Smiths Medical.

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